Second Podcast – Overview of Mitochondrial Errors


One of the most overlooked causes of ill health and poor functioning is mitochondrial error – AKA inborn errors of metabolism and cellular oxidation.

Oxidation occurs in a cell when an organism is forced to endure stresses beyond their capabilities, whether through environment, life stress, or poor nutrition, or any combination of these factors. Oxidation is further exacerbated when an individual forces themselves to “power through” their stress, and leads to transcription errors during cellular mitosis, leading to mutations in the cell DNA. All human beings experience oxidative stress, but not all are born with fully functioning mitochondria. Exposure to various environmental hazards increases mitochondrial oxidation as well.

Since the mitochondria is responsible for creating biological energy through the creation of ATP, when the normal transfer of electrons fails, while the body attempts to function normally, the individual suffers from all kinds of issues relating to biological energy loss, which may manifest as fatigue, pain, difficulty concentrating, muscle weakness, etc. Unfortunately, despite the fact that mitochondria literally power bodily systems, few physicians will think to address the possibility of a mitochondrial error and will instead prescribe stimulants to address the symptoms [of fatigue], which will lead to additional issues with regards to the already overtaxed organs, most notably the adrenal glands and kidneys and which do not address the underlying issue and may in fact add to the confusion surrounding proper diagnosis.

Mitochondrial deficits are best addressed through nutraceuticals and supplements such as coenzyme q10, riboflavin, magnesium taurate with vitamin C, and polyphenols. Polyphenols help to reduce cellular oxidation and the damage done to mitochondria by free radicals, while q10 improves mitochondrial function. Magnesium taurate is a special way of chelating magnesium with taurine, and is something I am very excited about as it can be used to close the gap in errors of metabolism during electron transfer in the Krebs’ cycle, which is where ATP is created from ADP. Riboflavin is a vitamin which is a member of the B family of vitamins and is essential for metabolic energy production.

Because organ damage is a common comorbid problem with inborn errors of metabolism, adaptogens and polyphenols which help support individual organ problems will be of assistance as well. Adaptogens are naturally occurring substances that help the body adapt to stress, like ginseng.

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